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Oral voclosporin: novel calcineurin inhibitor for treatment of noninfectious uveitis

Voclosporin, a novel immunomodulatory drug inhibiting the calcineurin enzyme, was developed to prevent organ graft rejection and to treat autoimmune diseases. The chemical structure of voclosporin is similar to that of cyclosporine A, with a difference in one amino acid, leading to superior calcineu...

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Detalles Bibliográficos
Autores principales: Roesel, Martin, Tappeiner, Christoph, Heiligenhaus, Arnd, Heinz, Carsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3180504/
https://www.ncbi.nlm.nih.gov/pubmed/21966207
http://dx.doi.org/10.2147/OPTH.S11125