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Cysteine modification reveals which subunits form the ligand binding site in human heteromeric 5-HT(3)AB receptors

ABSTRACT: The ligand binding site of Cys-loop receptors is formed by residues on the principal (+) and complementary (−) faces of adjacent subunits, but the subunits that constitute the binding pocket in many heteromeric receptors are not yet clear. To probe the subunits involved in ligand binding i...

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Detalles Bibliográficos
Autores principales: Thompson, A J, Price, K L, Lummis, S C R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Science Inc 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3180581/
https://www.ncbi.nlm.nih.gov/pubmed/21708905
http://dx.doi.org/10.1113/jphysiol.2011.208439