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Cysteine modification reveals which subunits form the ligand binding site in human heteromeric 5-HT(3)AB receptors
ABSTRACT: The ligand binding site of Cys-loop receptors is formed by residues on the principal (+) and complementary (−) faces of adjacent subunits, but the subunits that constitute the binding pocket in many heteromeric receptors are not yet clear. To probe the subunits involved in ligand binding i...
Autores principales: | Thompson, A J, Price, K L, Lummis, S C R |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Science Inc
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3180581/ https://www.ncbi.nlm.nih.gov/pubmed/21708905 http://dx.doi.org/10.1113/jphysiol.2011.208439 |
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