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The putative Notch ligand HyJagged is a transmembrane protein present in all cell types of adult Hydra and upregulated at the boundary between bud and parent

BACKGROUND: The Notch signalling pathway is conserved in pre-bilaterian animals. In the Cnidarian Hydra it is involved in interstitial stem cell differentiation and in boundary formation during budding. Experimental evidence suggests that in Hydra Notch is activated by presenilin through proteolytic...

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Detalles Bibliográficos
Autores principales: Prexl, Andrea, Münder, Sandra, Loy, Bernhard, Kremmer, Elisabeth, Tischer, Susanne, Böttger, Angelika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3180645/
https://www.ncbi.nlm.nih.gov/pubmed/21899759
http://dx.doi.org/10.1186/1471-2121-12-38