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Prevention of Prostate Cancer with Oleanane Synthetic Triterpenoid CDDO-Me in the TRAMP Mouse Model of Prostate Cancer

2-Cyano-3,12-dioxooleana-1,9(11)-dien-28-oic acid (CDDO), a synthetic analog of oleanolic acid, and its C28 methyl ester derivative (CDDO-Me), have shown potent antitumorigenic activity against a wide range of cancer cell lines, including prostate cancer cells in vitro, and inhibited the development...

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Detalles Bibliográficos
Autores principales: Gao, Xiaohua, Deeb, Dorrah, Liu, Yongbo, Arbab, Ali S., Divine, George W., Dulchavsky, Scott A., Gautam, Subhash C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3180910/
https://www.ncbi.nlm.nih.gov/pubmed/21961053
http://dx.doi.org/10.3390/cancers3033353