RasGrf1: genomic imprinting, VSELs, and aging

Increase in life span in RasGrf1-deficient mice revealed that RasGrf1 deficiency promotes longevity. Interestingly, RasGrf1 is one of parentally imprinted genes transcribed from paternally-derived chromosome. Erasure of its imprinting results in RasGrf1 downregulation and has been demonstrated in a...

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Detalles Bibliográficos
Autores principales: Ratajczak, Mariusz Z., Kucia, Magda, Liu, Rui, Shin, Dong-Myung, Bryndza, Ewa, Masternak, Michal M., Tarnowski, Maciej, Ratajczak, Janina, Bartke, Andrzej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2011
Materias:
Research Perspective
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3181169/
https://www.ncbi.nlm.nih.gov/pubmed/21765200

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3181169/
https://www.ncbi.nlm.nih.gov/pubmed/21765200

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