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Resveratrol Inhibits Growth of Orthotopic Pancreatic Tumors through Activation of FOXO Transcription Factors

BACKGROUND: The forkhead transcription factors of the O class (FOXO) play a direct role in cellular proliferation, oxidative stress response, and tumorigenesis. The objectives of this study were to examine whether FOXOs regulate antitumor activities of resveratrol in pancreatic cancer cells in vitro...

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Detalles Bibliográficos
Autores principales: Roy, Sanjit K., Chen, Qinghe, Fu, Junsheng, Shankar, Sharmila, Srivastava, Rakesh K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3181262/
https://www.ncbi.nlm.nih.gov/pubmed/21980390
http://dx.doi.org/10.1371/journal.pone.0025166