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miR-18a Impairs DNA Damage Response through Downregulation of Ataxia Telangiectasia Mutated (ATM) Kinase

The DNA damage response (DDR) encompasses multi-step processes by which cells evolve to sense DNA damage, transduce the signal and initiate the repair of damaged DNA. Ataxia Telangiectasia Mutated (ATM) Kinase, which functions as the primary sensor and transducer of DNA damage signal, has been demon...

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Detalles Bibliográficos
Autores principales: Song, Libing, Lin, Chuyong, Wu, Zhiqiang, Gong, Hui, Zeng, Yong, Wu, Jueheng, Li, Mengfeng, Li, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3181320/
https://www.ncbi.nlm.nih.gov/pubmed/21980462
http://dx.doi.org/10.1371/journal.pone.0025454