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Meet Me on the Other Side: Trans-Bilayer Modulation of a Model Voltage-Gated Ion Channel Activity by Membrane Electrostatics Asymmetry

While it is accepted that biomembrane asymmetry is generated by proteins and phospholipids distribution, little is known about how electric changes manifested in a monolayer influence functional properties of proteins localized on the opposite leaflet. Herein we used single-molecule electrophysiolog...

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Detalles Bibliográficos
Autores principales: Mereuta, Loredana, Asandei, Alina, Luchian, Tudor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3181326/
https://www.ncbi.nlm.nih.gov/pubmed/21980414
http://dx.doi.org/10.1371/journal.pone.0025276