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Activation of AMP-Activated Protein Kinase Is Required for Berberine-Induced Reduction of Atherosclerosis in Mice: The Role of Uncoupling Protein 2

AIMS: Berberine, a botanical alkaloid purified from Coptidis rhizoma, is reported to activate the AMP-activated protein kinase (AMPK). Whether AMPK is required for the protective effects of berberine in cardiovascular diseases remains unknown. This study was designed to determine whether AMPK is req...

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Detalles Bibliográficos
Autores principales: Wang, Qilong, Zhang, Miao, Liang, Bin, Shirwany, Najeeb, Zhu, Yi, Zou, Ming-Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3181327/
https://www.ncbi.nlm.nih.gov/pubmed/21980456
http://dx.doi.org/10.1371/journal.pone.0025436