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The Transcription Factor Ndt80 Does Not Contribute to Mrr1-, Tac1-, and Upc2-Mediated Fluconazole Resistance in Candida albicans

The pathogenic yeast Candida albicans can develop resistance to the widely used antifungal agent fluconazole, which inhibits ergosterol biosynthesis, by the overexpression of genes encoding multidrug efflux pumps or ergosterol biosynthesis enzymes. Zinc cluster transcription factors play a central r...

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Detalles Bibliográficos
Autores principales: Sasse, Christoph, Schillig, Rebecca, Dierolf, Franziska, Weyler, Michael, Schneider, Sabrina, Mogavero, Selene, Rogers, P. David, Morschhäuser, Joachim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3181345/
https://www.ncbi.nlm.nih.gov/pubmed/21980509
http://dx.doi.org/10.1371/journal.pone.0025623