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CD55 Deficiency Protects against Atherosclerosis in ApoE-Deficient Mice via C3a Modulation of Lipid Metabolism

Atherosclerosis, the leading cause of death in the Western world, is driven by chronic inflammation within the artery wall. Elements of the complement cascade are implicated in the pathogenesis, because complement proteins and their activation products are found in the atherosclerotic plaque. We exa...

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Detalles Bibliográficos
Autores principales: Lewis, Ruth D., Perry, Mark J., Guschina, Irina A., Jackson, Christopher L., Morgan, B. Paul, Hughes, Timothy R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Investigative Pathology 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3181373/
https://www.ncbi.nlm.nih.gov/pubmed/21816131
http://dx.doi.org/10.1016/j.ajpath.2011.06.015