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Reactive oxygen species initiate luminal but not basal cell death in cultured human mammary alveolar structures: a potential regulator of involution

Post-lactational involution of the mammary gland is initiated within days of weaning. Clearing of cells occurs by apoptosis of the milk-secreting luminal cells in the alveoli and through stromal tissue remodeling to return the gland almost completely to its pre-pregnant state. The pathways that spec...

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Detalles Bibliográficos
Autores principales: Thomas, E, Zeps, N, Rigby, P, Hartmann, P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3181416/
https://www.ncbi.nlm.nih.gov/pubmed/21814287
http://dx.doi.org/10.1038/cddis.2011.69