Celastrol inhibits aminoglycoside-induced ototoxicity via heat shock protein 32

Hearing loss is often caused by death of the mechanosensory hair cells of the inner ear. Hair cells are susceptible to death caused by aging, noise trauma, and ototoxic drugs, including the aminoglycoside antibiotics and the antineoplastic agent cisplatin. Ototoxic drugs result in permanent hearing...

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Detalles Bibliográficos
Autores principales: Francis, S P, Kramarenko, I I, Brandon, C S, Lee, F-S, Baker, T G, Cunningham, L L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3181421/
https://www.ncbi.nlm.nih.gov/pubmed/21866174
http://dx.doi.org/10.1038/cddis.2011.76

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3181421/
https://www.ncbi.nlm.nih.gov/pubmed/21866174
http://dx.doi.org/10.1038/cddis.2011.76

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