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Celastrol inhibits aminoglycoside-induced ototoxicity via heat shock protein 32
Hearing loss is often caused by death of the mechanosensory hair cells of the inner ear. Hair cells are susceptible to death caused by aging, noise trauma, and ototoxic drugs, including the aminoglycoside antibiotics and the antineoplastic agent cisplatin. Ototoxic drugs result in permanent hearing...
Autores principales: | Francis, S P, Kramarenko, I I, Brandon, C S, Lee, F-S, Baker, T G, Cunningham, L L |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3181421/ https://www.ncbi.nlm.nih.gov/pubmed/21866174 http://dx.doi.org/10.1038/cddis.2011.76 |
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