TNFR1 and TNFR2 regulate the extrinsic apoptotic pathway in myeloma cells by multiple mechanisms

The huge majority of myeloma cell lines express TNFR2 while a substantial subset of them failed to show TNFR1 expression. Stimulation of TNFR1 in the TNFR1-expressing subset of MM cell lines had no or only a very mild effect on cellular viability. Surprisingly, however, TNF stimulation enhanced cell...

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Detalles Bibliográficos
Autores principales: Rauert, H, Stühmer, T, Bargou, R, Wajant, H, Siegmund, D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3181423/
https://www.ncbi.nlm.nih.gov/pubmed/21850048
http://dx.doi.org/10.1038/cddis.2011.78

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3181423/
https://www.ncbi.nlm.nih.gov/pubmed/21850048
http://dx.doi.org/10.1038/cddis.2011.78

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