Cargando…

Vaccinia extracellular virions enter cells by macropinocytosis and acid-activated membrane rupture

Vaccinia virus (VACV), the model poxvirus, produces two types of infectious particles: mature virions (MVs) and extracellular virions (EVs). EV particles possess two membranes and therefore require an unusual cellular entry mechanism. By a combination of fluorescence and electron microscopy as well...

Descripción completa

Detalles Bibliográficos
Autores principales: Schmidt, Florian Ingo, Bleck, Christopher Karl Ernst, Helenius, Ari, Mercer, Jason
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Molecular Biology Organization 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3181475/
https://www.ncbi.nlm.nih.gov/pubmed/21792173
http://dx.doi.org/10.1038/emboj.2011.245