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The B-cell antigen receptor signals through a preformed transducer module of SLP65 and CIN85

Spleen tyrosine kinase Syk and its substrate SLP65 (also called BLNK) are proximal signal transducer elements of the B-cell antigen receptor (BCR). Yet, our understanding of signal initiation and processing is limited owing to the incomplete list of SLP65 interaction partners and our ignorance of th...

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Detalles Bibliográficos
Autores principales: Oellerich, Thomas, Bremes, Vanessa, Neumann, Konstantin, Bohnenberger, Hanibal, Dittmann, Kai, Hsiao, He-Hsuan, Engelke, Michael, Schnyder, Tim, Batista, Facundo D, Urlaub, Henning, Wienands, Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Molecular Biology Organization 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3181483/
https://www.ncbi.nlm.nih.gov/pubmed/21822214
http://dx.doi.org/10.1038/emboj.2011.251