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Are cross-species measures of sensorimotor gating useful for the discovery of procognitive cotreatments for schizophrenia?

Prepulse inhibition of startle (PPI), a measure of sensorimotor gating used to identify antipsychotics, is reduced in schizophrenia patients and in rodents treated with dopamine agonists or glutamate antagonists. The National institute of Menial Health (NIMH)-funded Measurement And Treatment Researc...

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Detalles Bibliográficos
Autor principal: Geyer, Mark A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Les Laboratoires Servier 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3181759/
https://www.ncbi.nlm.nih.gov/pubmed/16640109