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Expression profiling of drug response - from genes to pathways

Understanding individual response to a drug -what determines its efficacy and tolerability -is the major bottleneck in current drug development and clinical trials. Intracellular response and metabolism, for example through cytochrome P-450 enzymes, may either enhance or decrease the effect of diffe...

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Detalles Bibliográficos
Autores principales: Herwig, Ralf, Lehrach, Hans
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Les Laboratoires Servier 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3181826/
https://www.ncbi.nlm.nih.gov/pubmed/17117610