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Expression profiling of drug response - from genes to pathways
Understanding individual response to a drug -what determines its efficacy and tolerability -is the major bottleneck in current drug development and clinical trials. Intracellular response and metabolism, for example through cytochrome P-450 enzymes, may either enhance or decrease the effect of diffe...
Autores principales: | Herwig, Ralf, Lehrach, Hans |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Les Laboratoires Servier
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3181826/ https://www.ncbi.nlm.nih.gov/pubmed/17117610 |
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