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Chemokine nitration prevents intratumoral infiltration of antigen-specific T cells

Tumor-promoted constraints negatively affect cytotoxic T lymphocyte (CTL) trafficking to the tumor core and, as a result, inhibit tumor killing. The production of reactive nitrogen species (RNS) within the tumor microenvironment has been reported in mouse and human cancers. We describe a novel RNS-d...

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Detalles Bibliográficos
Autores principales: Molon, Barbara, Ugel, Stefano, Del Pozzo, Federica, Soldani, Cristiana, Zilio, Serena, Avella, Debora, De Palma, Antonella, Mauri, PierLuigi, Monegal, Ana, Rescigno, Maria, Savino, Benedetta, Colombo, Piergiuseppe, Jonjic, Nives, Pecanic, Sanja, Lazzarato, Loretta, Fruttero, Roberta, Gasco, Alberto, Bronte, Vincenzo, Viola, Antonella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3182051/
https://www.ncbi.nlm.nih.gov/pubmed/21930770
http://dx.doi.org/10.1084/jem.20101956