Critical role of Bcl11b in suppressor function of T regulatory cells and prevention of inflammatory bowel disease

Dysregulated CD4(+) T cell responses and alterations in T regulatory cells (T(reg) cells) play a critical role in autoimmune diseases, including inflammatory bowel disease (IBD). The current study demonstrates that removal of Bcl11b at the double-positive stage of T cell development or only in T(reg...

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Detalles Bibliográficos
Autores principales: VanValkenburgh, Jeffrey, Albu, Diana I., Bapanpally, Chandra, Casanova, Sarah, Califano, Danielle, Jones, David M., Ignatowicz, Leszek, Kawamoto, Shimpei, Fagarasan, Sidonia, Jenkins, Nancy A., Copeland, Neal G., Liu, Pentao, Avram, Dorina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3182057/
https://www.ncbi.nlm.nih.gov/pubmed/21875956
http://dx.doi.org/10.1084/jem.20102683

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3182057/
https://www.ncbi.nlm.nih.gov/pubmed/21875956
http://dx.doi.org/10.1084/jem.20102683

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