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Cannabinoid receptor 2 positions and retains marginal zone B cells within the splenic marginal zone

Specialized B cells residing in the splenic marginal zone (MZ) continuously survey the blood for antigens and are important for immunity to systemic infections. However, the cues that uniquely attract cells to the MZ have not been defined. Previous work demonstrated that mice deficient in cannabinoi...

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Detalles Bibliográficos
Autores principales: Muppidi, Jagan R., Arnon, Tal I., Bronevetsky, Yelena, Veerapen, Natacha, Tanaka, Masato, Besra, Gurdyal S., Cyster, Jason G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3182059/
https://www.ncbi.nlm.nih.gov/pubmed/21875957
http://dx.doi.org/10.1084/jem.20111083