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Notch signaling inhibits hepatocellular carcinoma following inactivation of the RB pathway

Hepatocellular carcinoma (HCC) is the third cancer killer worldwide with >600,000 deaths every year. Although the major risk factors are known, therapeutic options in patients remain limited in part because of our incomplete understanding of the cellular and molecular mechanisms influencing HCC d...

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Detalles Bibliográficos
Autores principales: Viatour, Patrick, Ehmer, Ursula, Saddic, Louis A., Dorrell, Craig, Andersen, Jesper B., Lin, Chenwei, Zmoos, Anne-Flore, Mazur, Pawel K., Schaffer, Bethany E., Ostermeier, Austin, Vogel, Hannes, Sylvester, Karl G., Thorgeirsson, Snorri S., Grompe, Markus, Sage, Julien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3182062/
https://www.ncbi.nlm.nih.gov/pubmed/21875955
http://dx.doi.org/10.1084/jem.20110198