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Notch signaling inhibits hepatocellular carcinoma following inactivation of the RB pathway
Hepatocellular carcinoma (HCC) is the third cancer killer worldwide with >600,000 deaths every year. Although the major risk factors are known, therapeutic options in patients remain limited in part because of our incomplete understanding of the cellular and molecular mechanisms influencing HCC d...
Autores principales: | Viatour, Patrick, Ehmer, Ursula, Saddic, Louis A., Dorrell, Craig, Andersen, Jesper B., Lin, Chenwei, Zmoos, Anne-Flore, Mazur, Pawel K., Schaffer, Bethany E., Ostermeier, Austin, Vogel, Hannes, Sylvester, Karl G., Thorgeirsson, Snorri S., Grompe, Markus, Sage, Julien |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3182062/ https://www.ncbi.nlm.nih.gov/pubmed/21875955 http://dx.doi.org/10.1084/jem.20110198 |
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