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Host type I IFN signals are required for antitumor CD8(+) T cell responses through CD8α(+) dendritic cells
Despite lack of tumor control in many models, spontaneous T cell priming occurs frequently in response to a growing tumor. However, the innate immune mechanisms that promote natural antitumor T cell responses are undefined. In human metastatic melanoma, there was a correlation between a type I inter...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3182064/ https://www.ncbi.nlm.nih.gov/pubmed/21930765 http://dx.doi.org/10.1084/jem.20101159 |