Hematological Changes as Prognostic Indicators of Survival: Similarities Between Gottingen Minipigs, Humans, and Other Large Animal Models

BACKGROUND: The animal efficacy rule addressing development of drugs for selected disease categories has pointed out the need to develop alternative large animal models. Based on this rule, the pathophysiology of the disease in the animal model must be well characterized and must reflect that in hum...

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Detalles Bibliográficos
Autores principales: Moroni, Maria, Lombardini, Eric, Salber, Rudolph, Kazemzedeh, Mehdi, Nagy, Vitaly, Olsen, Cara, Whitnall, Mark H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3182184/
https://www.ncbi.nlm.nih.gov/pubmed/21969873
http://dx.doi.org/10.1371/journal.pone.0025210

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3182184/
https://www.ncbi.nlm.nih.gov/pubmed/21969873
http://dx.doi.org/10.1371/journal.pone.0025210

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