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Autocrine Netrin Function Inhibits Glioma Cell Motility and Promotes Focal Adhesion Formation

Deregulation of mechanisms that control cell motility plays a key role in tumor progression by promoting tumor cell dissemination. Secreted netrins and their receptors, Deleted in Colorectal Cancer (DCC), neogenin, and the UNC5 homologues, regulate cell and axon migration, cell adhesion, and tissue...

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Detalles Bibliográficos
Autores principales: Jarjour, Andrew A., Durko, Margaret, Luk, Tamarah L., Marçal, Nathalie, Shekarabi, Masoud, Kennedy, Timothy E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3182204/
https://www.ncbi.nlm.nih.gov/pubmed/21980448
http://dx.doi.org/10.1371/journal.pone.0025408