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Intracerebral Administration of Recombinant Rabies Virus Expressing GM-CSF Prevents the Development of Rabies after Infection with Street Virus

Recently it was found that prior immunization with recombinant rabies virus (RABV) expressing granulocyte-macrophage colony-stimulating factor (GM-CSF) (LBNSE-GM-CSF) resulted in high innate/adaptive immune responses and protection against challenge with virulent RABV (Wen et al., JVI, 2011). In thi...

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Detalles Bibliográficos
Autores principales: Wang, Hualei, Zhang, Guoqing, Wen, Yongjun, Yang, Songtao, Xia, Xianzhu, Fu, Zhen F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3182207/
https://www.ncbi.nlm.nih.gov/pubmed/21980450
http://dx.doi.org/10.1371/journal.pone.0025414