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Bacteriophage-Resistant Mutants in Yersinia pestis: Identification of Phage Receptors and Attenuation for Mice

BACKGROUND: Bacteriophages specific for Yersinia pestis are routinely used for plague diagnostics and could be an alternative to antibiotics in case of drug-resistant plague. A major concern of bacteriophage therapy is the emergence of phage-resistant mutants. The use of phage cocktails can overcome...

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Detalles Bibliográficos
Autores principales: Filippov, Andrey A., Sergueev, Kirill V., He, Yunxiu, Huang, Xiao-Zhe, Gnade, Bryan T., Mueller, Allen J., Fernandez-Prada, Carmen M., Nikolich, Mikeljon P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3182234/
https://www.ncbi.nlm.nih.gov/pubmed/21980477
http://dx.doi.org/10.1371/journal.pone.0025486