Kv7 Channels Can Function without Constitutive Calmodulin Tethering

M-channels are voltage-gated potassium channels composed of Kv7.2-7.5 subunits that serve as important regulators of neuronal excitability. Calmodulin binding is required for Kv7 channel function and mutations in Kv7.2 that disrupt calmodulin binding cause Benign Familial Neonatal Convulsions (BFNC)...

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Detalles Bibliográficos
Autores principales: Gómez-Posada, Juan Camilo, Aivar, Paloma, Alberdi, Araitz, Alaimo, Alessandro, Etxeberría, Ainhoa, Fernández-Orth, Juncal, Zamalloa, Teresa, Roura-Ferrer, Meritxell, Villace, Patricia, Areso, Pilar, Casis, Oscar, Villarroel, Alvaro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3182250/
https://www.ncbi.nlm.nih.gov/pubmed/21980481
http://dx.doi.org/10.1371/journal.pone.0025508

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3182250/
https://www.ncbi.nlm.nih.gov/pubmed/21980481
http://dx.doi.org/10.1371/journal.pone.0025508

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