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Potassium-selective block of barium permeation through single KcsA channels

Ba(2+), a doubly charged analogue of K(+), specifically blocks K(+) channels by virtue of electrostatic stabilization in the permeation pathway. Ba(2+) block is used here as a tool to determine the equilibrium binding affinity for various monovalent cations at specific sites in the selectivity filte...

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Detalles Bibliográficos
Autores principales: Piasta, Kene N., Theobald, Douglas L., Miller, Christopher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3182450/
https://www.ncbi.nlm.nih.gov/pubmed/21911483
http://dx.doi.org/10.1085/jgp.201110684