Foxp3(+) follicular regulatory T cells control T follicular helper cells and the germinal center response

Follicular helper (T(FH)) cells provide crucial signals to germinal center B cells undergoing somatic hypermutation and selection that results in affinity maturation. Tight control of T(FH) numbers maintains self-tolerance. We describe a population of Foxp3(+)Blimp-1(+)CD4(+) T cells constituting 10...

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Detalles Bibliográficos
Autores principales: Linterman, Michelle A., Pierson, Wim, Lee, Sau K., Kallies, Axel, Kawamoto, Shimpei, Rayner, Tim F., Srivastava, Monika, Divekar, Devina P., Beaton, Laura, Hogan, Jennifer J., Fagarasan, Sidonia, Liston, Adrian, Smith, Kenneth G. C., Vinuesa, Carola G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3182542/
https://www.ncbi.nlm.nih.gov/pubmed/21785433
http://dx.doi.org/10.1038/nm.2425

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3182542/
https://www.ncbi.nlm.nih.gov/pubmed/21785433
http://dx.doi.org/10.1038/nm.2425

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