Cargando…

Foxp3(+) follicular regulatory T cells control T follicular helper cells and the germinal center response

Follicular helper (T(FH)) cells provide crucial signals to germinal center B cells undergoing somatic hypermutation and selection that results in affinity maturation. Tight control of T(FH) numbers maintains self-tolerance. We describe a population of Foxp3(+)Blimp-1(+)CD4(+) T cells constituting 10...

Descripción completa

Detalles Bibliográficos
Autores principales:	Linterman, Michelle A., Pierson, Wim, Lee, Sau K., Kallies, Axel, Kawamoto, Shimpei, Rayner, Tim F., Srivastava, Monika, Divekar, Devina P., Beaton, Laura, Hogan, Jennifer J., Fagarasan, Sidonia, Liston, Adrian, Smith, Kenneth G. C., Vinuesa, Carola G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2011
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3182542/ https://www.ncbi.nlm.nih.gov/pubmed/21785433 http://dx.doi.org/10.1038/nm.2425

Ejemplares similares

Follicular helper T cells are required for systemic autoimmunity
por: Linterman, Michelle A., et al.
Publicado: (2009)

MicroRNA-146a regulates ICOS–ICOSL signalling to limit accumulation of T follicular helper cells and germinal centres
por: Pratama, Alvin, et al.
Publicado: (2015)

Can follicular helper T cells be targeted to improve vaccine efficacy?
por: Linterman, Michelle A., et al.
Publicado: (2016)

Follicular Regulatory T Cells Can Access the Germinal Center Independently of CXCR5
por: Vanderleyden, Ine, et al.
Publicado: (2020)

Neonatal T Follicular Helper Cells Are Lodged in a Pre-T Follicular Helper Stage Favoring Innate Over Adaptive Germinal Center Responses
por: Mastelic-Gavillet, Beatris, et al.
Publicado: (2019)

The Calcineurin Inhibitor Tacrolimus Specifically Suppresses Human T Follicular Helper Cells
por: Wallin, Elizabeth F., et al.
Publicado: (2018)

Rejuvenating conventional dendritic cells and T follicular helper cell formation after vaccination
por: Stebegg, Marisa, et al.
Publicado: (2020)

Follicular helper T cells progressively differentiate to regulate the germinal center response
por: Weinstein, Jason S., et al.
Publicado: (2016)

Germinal Center Cells Turning to the Dark Side: Neoplasms of B Cells, Follicular Helper T Cells, and Follicular Dendritic Cells
por: Munguía-Fuentes, Rosario, et al.
Publicado: (2021)

Attenuation of AMPK signaling by ROQUIN promotes T follicular helper cell formation
por: Ramiscal, Roybel R, et al.
Publicado: (2015)

Loss of Bcl-6-Expressing T Follicular Helper Cells and Germinal Centers in COVID-19
por: Kaneko, Naoki, et al.
Publicado: (2020)

Interleukin-1 in the Response of Follicular Helper and Follicular Regulatory T Cells
por: Ritvo, Paul-Gydéon, et al.
Publicado: (2019)

T follicular helper cells and T follicular regulatory cells in autoimmune diseases
por: Qi, Jingjing, et al.
Publicado: (2023)

Life of T Follicular Helper Cells
por: Suh, Woong-Kyung
Publicado: (2015)

Sphingosine-1-phosphate receptor 2 is critical for follicular helper T cell retention in germinal centers
por: Moriyama, Saya, et al.
Publicado: (2014)

Impaired HA-specific T follicular helper cell and antibody responses to influenza vaccination are linked to inflammation in humans
por: Hill, Danika L, et al.
Publicado: (2021)

Ageing promotes early T follicular helper cell differentiation by modulating expression of RBPJ
por: Webb, Louise M. C., et al.
Publicado: (2021)

T follicular helper cells: a potential therapeutic target in follicular lymphoma
por: Ochando, Jordi, et al.
Publicado: (2017)

T follicular helper and T follicular regulatory cells have different TCR specificity
por: Maceiras, Ana Raquel, et al.
Publicado: (2017)

Follicular regulatory T cells impair follicular T helper cells in HIV and SIV infection
por: Miles, Brodie, et al.
Publicado: (2015)

Helios Is Associated with CD4 T Cells Differentiating to T Helper 2 and Follicular Helper T Cells In Vivo Independently of Foxp3 Expression
por: Serre, Karine, et al.
Publicado: (2011)

The origins, function, and regulation of T follicular helper cells
por: Ma, Cindy S., et al.
Publicado: (2012)

Regulation of T follicular helper cells by ICOS
por: Hutloff, Andreas
Publicado: (2015)

Follicular helper T cell in immunity and autoimmunity
por: Mesquita, D., et al.
Publicado: (2016)

T Follicular Helper Cells in Autoimmune Disorders
por: Gensous, Noémie, et al.
Publicado: (2018)

Primary cutaneous T‐follicular helper lymphoma
por: Fenu, Elena M., et al.
Publicado: (2023)

The Role of CD4+ T Follicular Helper Cells in HIV Infection: From the Germinal Center to the Periphery
por: Thornhill, John Patrick, et al.
Publicado: (2017)

Impact of Chronic HIV/SIV Infection on T Follicular Helper Cell Subsets and Germinal Center Homeostasis
por: Graff-Dubois, Stéphanie, et al.
Publicado: (2016)

Continually recruited naïve T cells contribute to the follicular helper and regulatory T cell pools in germinal centers
por: Merkenschlager, Julia, et al.
Publicado: (2023)

P1215: CHARACTERIZATION AND CLINICAL SIGNIFICANCE OF T FOLLICULAR HELPER SUBSETS IN FOLLICULAR LYMPHOMA
por: Yang, Zhi-Zhang, et al.
Publicado: (2023)

PPARγ Negatively Regulates T Cell Activation to Prevent Follicular Helper T Cells and Germinal Center Formation
por: Park, Hong-Jai, et al.
Publicado: (2014)

Nucleoside-modified mRNA vaccines induce potent T follicular helper and germinal center B cell responses
por: Pardi, Norbert, et al.
Publicado: (2018)

IL-21 acts directly on B cells to regulate Bcl-6 expression and germinal center responses
por: Linterman, Michelle A., et al.
Publicado: (2010)

Spatial dysregulation of T follicular helper cells impairs vaccine responses in aging
por: Silva-Cayetano, Alyssa, et al.
Publicado: (2023)

Germinal Center B Cell Depletion Diminishes CD4(+) Follicular T Helper Cells in Autoimmune Mice
por: Yusuf, Isharat, et al.
Publicado: (2014)

Regulation of Autoimmune Germinal Center Reactions in Lupus-Prone BXD2 Mice by Follicular Helper T Cells
por: Kim, Young Uk, et al.
Publicado: (2015)

Germinal Center B Cell and T Follicular Helper Cell Responses to Viral Vector and Protein-in-Adjuvant Vaccines
por: Wang, Chuan, et al.
Publicado: (2016)

Context-Dependent Role for T-bet in T Follicular Helper Differentiation and Germinal Center Function following Viral Infection
por: Sheikh, Amania A., et al.
Publicado: (2019)

Imbalance of Circulatory T Follicular Helper and T Follicular Regulatory Cells in Patients with ANCA-Associated Vasculitis
por: Xu, Ying, et al.
Publicado: (2019)

The Role of T Follicular Helper Cells and T Follicular Regulatory Cells in the Pathogenesis of Autoimmune Hemolytic Anemia
por: Gao, Yuhan, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_an4lakhf4sm0tpsv3liortfhma