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Energy Landscape and Global Optimization for a Frustrated Model Protein

[Image: see text] The three-color (BLN) 69-residue model protein was designed to exhibit frustrated folding. We investigate the energy landscape of this protein using disconnectivity graphs and compare it to a Go̅ model, which is designed to reduce the frustration by removing all non-native attracti...

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Detalles Bibliográficos
Autores principales: Oakley, Mark T., Wales, David J., Johnston, Roy L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2011
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3182752/
https://www.ncbi.nlm.nih.gov/pubmed/21866973
http://dx.doi.org/10.1021/jp207246m