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The Role of Immune Correlates and Surrogate Markers in the Development of Vaccines and Immunotherapies for Plague

One of the difficulties in developing countermeasures to biothreat agents is the challenge inherent in demonstrating their efficacy in man. Since the first publication of the Animal Rule by the FDA, there has been increased discussion of potential correlates of protection in animal models and their...

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Detalles Bibliográficos
Autor principal: Williamson, E. D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3182760/
https://www.ncbi.nlm.nih.gov/pubmed/21991451
http://dx.doi.org/10.1155/2012/365980