Keratinocyte Secretion of Cyclophilin B via the Constitutive Pathway Is Regulated through Its Cyclosporin-Binding Site

Cyclophilin B (CypB) is an endoplasmic reticulum (ER)-resident member of the cyclophilin family of proteins that bind cyclosporin A (CsA). We report that as in other cell types, CypB trafficked from the ER and was secreted by keratinocytes into the media in response to CsA. Concentrations as low as...

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Detalles Bibliográficos
Autores principales: Fearon, Paula, Lonsdale-Eccles, Ann A, Ross, O Kehinde, Todd, Carole, Sinha, Aparna, Allain, Fabrice, Reynolds, Nick J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3182837/
https://www.ncbi.nlm.nih.gov/pubmed/21270823
http://dx.doi.org/10.1038/jid.2010.415

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3182837/
https://www.ncbi.nlm.nih.gov/pubmed/21270823
http://dx.doi.org/10.1038/jid.2010.415

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