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Increased betulinic acid induced cytotoxicity and radiosensitivity in glioma cells under hypoxic conditions

BACKGROUND: Betulinic acid (BA) is a novel antineoplastic agent under evaluation for tumor therapy. Because of the selective cytotoxic effects of BA in tumor cells (including gliomas), the combination of this agent with conservative therapies (such as radiotherapy and chemotherapy) may be useful. Pr...

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Detalles Bibliográficos
Autores principales: Bache, Matthias, Zschornak, Martin P, Passin, Sarina, Keßler, Jacqueline, Wichmann, Henri, Kappler, Matthias, Paschke, Reinhard, Kaluđerović, Goran N, Kommera, Harish, Taubert, Helge, Vordermark, Dirk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3182903/
https://www.ncbi.nlm.nih.gov/pubmed/21906280
http://dx.doi.org/10.1186/1748-717X-6-111