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Increased betulinic acid induced cytotoxicity and radiosensitivity in glioma cells under hypoxic conditions
BACKGROUND: Betulinic acid (BA) is a novel antineoplastic agent under evaluation for tumor therapy. Because of the selective cytotoxic effects of BA in tumor cells (including gliomas), the combination of this agent with conservative therapies (such as radiotherapy and chemotherapy) may be useful. Pr...
Autores principales: | Bache, Matthias, Zschornak, Martin P, Passin, Sarina, Keßler, Jacqueline, Wichmann, Henri, Kappler, Matthias, Paschke, Reinhard, Kaluđerović, Goran N, Kommera, Harish, Taubert, Helge, Vordermark, Dirk |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3182903/ https://www.ncbi.nlm.nih.gov/pubmed/21906280 http://dx.doi.org/10.1186/1748-717X-6-111 |
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