Activation of matrix metalloproteinases following anti-Aβ immunotherapy; implications for microhemorrhage occurrence

BACKGROUND: Anti-Aβ immunotherapy is a promising approach to the prevention and treatment of Alzheimer's disease (AD) currently in clinical trials. There is extensive evidence, both in mice and humans that a significant adverse event is the occurrence of microhemorrhages. Also, vasogenic edema...

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Detalles Bibliográficos
Autores principales: Wilcock, Donna M, Morgan, Dave, Gordon, Marcia N, Taylor, Tiffany L, Ridnour, Lisa A, Wink, David A, Colton, Carol A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3182918/
https://www.ncbi.nlm.nih.gov/pubmed/21906275
http://dx.doi.org/10.1186/1742-2094-8-115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3182918/
https://www.ncbi.nlm.nih.gov/pubmed/21906275
http://dx.doi.org/10.1186/1742-2094-8-115

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