The Human Papillomavirus E6 Oncogene Represses a Cell Adhesion Pathway and Disrupts Focal Adhesion through Degradation of TAp63β upon Transformation

Cervical carcinomas result from cellular transformation by the human papillomavirus (HPV) E6 and E7 oncogenes which are constitutively expressed in cancer cells. The E6 oncogene degrades p53 thereby modulating a large set of p53 target genes as shown previously in the cervical carcinoma cell line He...

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Detalles Bibliográficos
Autores principales: Ben Khalifa, Youcef, Teissier, Sébastien, Tan, Meng-Kwang Marcus, Phan, Quang Tien, Daynac, Mathieu, Wong, Wei Qi, Thierry, Françoise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3182928/
https://www.ncbi.nlm.nih.gov/pubmed/21980285
http://dx.doi.org/10.1371/journal.ppat.1002256

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3182928/
https://www.ncbi.nlm.nih.gov/pubmed/21980285
http://dx.doi.org/10.1371/journal.ppat.1002256

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