Strain Specific Resistance to Murine Scrapie Associated with a Naturally Occurring Human Prion Protein Polymorphism at Residue 171

Transmissible spongiform encephalopathies (TSE) or prion diseases are neurodegenerative disorders associated with conversion of normal host prion protein (PrP) to a misfolded, protease-resistant form (PrPres). Genetic variations of prion protein in humans and animals can alter susceptibility to both...

Descripción completa

Detalles Bibliográficos
Autores principales: Striebel, James F., Race, Brent, Meade-White, Kimberly D., LaCasse, Rachel, Chesebro, Bruce
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3182929/
https://www.ncbi.nlm.nih.gov/pubmed/21980292
http://dx.doi.org/10.1371/journal.ppat.1002275

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3182929/
https://www.ncbi.nlm.nih.gov/pubmed/21980292
http://dx.doi.org/10.1371/journal.ppat.1002275

Ejemplares similares