High-Resolution Phenotypic Profiling Defines Genes Essential for Mycobacterial Growth and Cholesterol Catabolism

The pathways that comprise cellular metabolism are highly interconnected, and alterations in individual enzymes can have far-reaching effects. As a result, global profiling methods that measure gene expression are of limited value in predicting how the loss of an individual function will affect the...

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Detalles Bibliográficos
Autores principales: Griffin, Jennifer E., Gawronski, Jeffrey D., DeJesus, Michael A., Ioerger, Thomas R., Akerley, Brian J., Sassetti, Christopher M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3182942/
https://www.ncbi.nlm.nih.gov/pubmed/21980284
http://dx.doi.org/10.1371/journal.ppat.1002251

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3182942/
https://www.ncbi.nlm.nih.gov/pubmed/21980284
http://dx.doi.org/10.1371/journal.ppat.1002251

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