Phosphorylation of the Ndc80 complex protein, HEC1, by Nek2 kinase modulates chromosome alignment and signaling of the spindle assembly checkpoint

The spindle assemble checkpoint (SAC) is critical for accurate chromosome segregation. Hec1 contributes to chromosome segregation in part by mediating SAC signaling and chromosome alignment. However, the molecular mechanism by which Hec1 modulates checkpoint signaling and alignment remains poorly un...

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Detalles Bibliográficos
Autores principales: Wei, Randy, Ngo, Bryan, Wu, Guikai, Lee, Wen-Hwa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2011
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3183014/
https://www.ncbi.nlm.nih.gov/pubmed/21832156
http://dx.doi.org/10.1091/mbc.E11-01-0012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3183014/
https://www.ncbi.nlm.nih.gov/pubmed/21832156
http://dx.doi.org/10.1091/mbc.E11-01-0012

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