Cargando…

Retrolinkin cooperates with endophilin A1 to mediate BDNF–TrkB early endocytic trafficking and signaling from early endosomes

Brain-derived neurotrophic factor (BDNF) binds to its cell surface receptor TrkB to regulate differentiation, development, synaptic plasticity, and functional maintenance of neuronal cells. Binding of BDNF triggers TrkB dimerization and autophosphorylation, which provides docking sites for adaptor p...

Descripción completa

Detalles Bibliográficos
Autores principales: Fu, Xiuping, Yang, Yanrui, Xu, Chenchang, Niu, Yang, Chen, Tielin, Zhou, Qin, Liu, Jia-Jia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3183022/
https://www.ncbi.nlm.nih.gov/pubmed/21849472
http://dx.doi.org/10.1091/mbc.E11-04-0308