Mapping of ESE-1 subdomains required to initiate mammary epithelial cell transformation via a cytoplasmic mechanism

BACKGROUND: The ETS family transcription factor ESE-1 is often overexpressed in human breast cancer. ESE-1 initiates transformation of MCF-12A cells via a non-transcriptional, cytoplasmic process that is mediated by a unique 40-amino acid serine and aspartic acid rich (SAR) subdomain, whereas, ESE-1...

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Detalles Bibliográficos
Autores principales: Prescott, Jason D, Poczobutt, Joanna M, Tentler, John J, Walker, Darius M, Gutierrez-Hartmann, Arthur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3183030/
https://www.ncbi.nlm.nih.gov/pubmed/21871131
http://dx.doi.org/10.1186/1476-4598-10-103

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3183030/
https://www.ncbi.nlm.nih.gov/pubmed/21871131
http://dx.doi.org/10.1186/1476-4598-10-103

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