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Determinants of Nucleotide-Binding Selectivity of Malic Enzyme

Malic enzymes have high cofactor selectivity. An isoform-specific distribution of residues 314, 346, 347 and 362 implies that they may play key roles in determining the cofactor specificity. Currently, Glu314, Ser346, Lys347 and Lys362 in human c-NADP-ME were changed to the corresponding residues of...

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Detalles Bibliográficos
Autores principales: Hsieh, Ju-Yi, Chen, Meng-Chun, Hung, Hui-Chih
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3183043/
https://www.ncbi.nlm.nih.gov/pubmed/21980421
http://dx.doi.org/10.1371/journal.pone.0025312