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The SOCS2 Ubiquitin Ligase Complex Regulates Growth Hormone Receptor Levels

Growth Hormone is essential for the regulation of growth and the homeostatic control of intermediary metabolism. GH actions are mediated by the Growth Hormone Receptor; a member of the cytokine receptor super family that signals chiefly through the JAK2/STAT5 pathway. Target tissue responsiveness to...

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Detalles Bibliográficos
Autores principales: Vesterlund, Mattias, Zadjali, Fahad, Persson, Torbjörn, Nielsen, Michael Lund, Kessler, Benedikt M., Norstedt, Gunnar, Flores-Morales, Amilcar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3183054/
https://www.ncbi.nlm.nih.gov/pubmed/21980433
http://dx.doi.org/10.1371/journal.pone.0025358