Cargando…
The N-Terminal, Polybasic Region Is Critical for Prion Protein Neuroprotective Activity
Several lines of evidence suggest that the normal form of the prion protein, PrP(C), exerts a neuroprotective activity against cellular stress or toxicity. One of the clearest examples of such activity is the ability of wild-type PrP(C) to suppress the spontaneous neurodegenerative phenotype of tran...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2011
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3183058/ https://www.ncbi.nlm.nih.gov/pubmed/21980526 http://dx.doi.org/10.1371/journal.pone.0025675 |